Glycopyrrolate is an anticholinergic drug, and this means that there are patients with some conditions where glycopyrrolate should be avoided or used cautiously. Bevespi should be used cautiously in those with impaired kidney or liver function. Though COPD doesn’t typically affect children, Bevespi is not indicated for children or women who are pregnant or breastfeeding. There are some patients for whom Bevespi may not be the ideal choice.
Patients on Bevespi also had to use short-acting rescue bronchodilator inhalers like albuterol less frequently. Bevespi consistently provided better results measured by forced expiratory volume (FEV) as compared to each drug component used alone or as compared to a placebo. The manufacturer of Bevespi, AstraZeneca, trialed the combination of glycopyrrolate and formoterol after evaluating the results of each drug on COPD symptoms alone. Fortunately, the symptoms of COPD can often be managed with medications like Bevespi and allow people to live relatively normal lives with COPD along with other healthy lifestyle changes.
It can prevent even the most basic of life functions like walking, cooking, or bathing. The presence of thick mucus makes it hard to move air in and through the airways. This is characterized by constant irritation and inflammation of the lining of the airways. The second condition of COPD is chronic bronchitis. In emphysema, these sac walls become damaged, and they can no longer contract and expand effectively to move air efficiently. The walls of the sacs need to be “stretchy” and healthy in order for this to occur. Your lungs have many air sacs, and the functionality of them is to contract and expand to move air. So what is COPD? COPD is comprised of two conditions, and most people who have COPD display symptoms of both to some varying extent.
It is the fourth leading cause of disability in the United States according to the Centers for Disease Control and Prevention (CDC), and this has effects on society as a whole including the workforce and healthcare system. In the United States alone, COPD is estimated to affect 15 million adults. Bevespi is not approved by the Food and Drug Administration (FDA) for the treatment of asthma.Įffective treatment of COPD is an important factor to many. Although they work via their own distinct mechanisms, LAMAs and LABAs ultimately lead to bronchodilation, or an opening and broadening of the airways. It is the combination of two drugs, glycopyrrolate, a long-acting muscarinic antagonist (LAMA), and formoterol fumarate, a long-acting beta-agonist (LABA).
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fda.Compare Bevespi alternatives | LABA and ICS combinations | LABA, LAMA, and ICS combinations | LAMAs | Oral corticosteroids | Inhaled short-acting muscarinic antagonists | Natural alternatives | How to switch medsīevespi Aerosphere is an inhaled brand-name prescription drug product used in the maintenance treatment of chronic obstructive pulmonary disease (COPD).
Tools-for-the-Public/Drug-Guide/Long-Acting-Beta-Agonists-(LABAs) Drug interactions with oral inhaled medications. You can learn more about how we ensure our content is accurate and current by reading our editorial policy. Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations.
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